What are stem cells?

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Stem cells have the potential to develop into various cells in the body. After stem cell division, it can repair other cells. It can replace the other cells that has deteriorated for the body to be able to rehabilitate and stay in a better condition.

What are stem cells?

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Stem cells have the remarkable potential to develop into many different cell types in the body. They can divided into 2 types of cells which are:

1. Stem Cells that has the origin of human embryo, these cells can be transformed into other cells in the body without limitations. such as brain cell, skin cell, muscle cell, heart cell, or blood cell, etc.

2. Stem Cells that is formed by a tissue, the stem cells can be changed into a more limited types of cells, it cannot be transformed into all cells in the body. Such as stem cells of blood can become red blood cell, white blood cells, or plasma, while stem cells of the skin can be changed into skin cells.

What can stem cells be used to cure?

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Stem cells can be used to cure diseases that is related to blood, for other diseases, there is not yet enough studies to support the operation. However, there are many ongoing studies that the future promises a more variety of stem cells usage. For now stem cells are used to treat:

Leukemia
Thalassemia
Congenital Immune Deficiency Diseases
Some cancers such as breast cancer, kidney cancer, etc.
Hemolysis
SLE Disease
Bone Marrow Atrophy
Etc.

Where do stem cells come from?

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There are several sources of stem cells. Pluripotent stem cells can be isolated from human embryos that are a few days old. Cells from these embryos can be used to create pluripotent stem cell "lines" cell cultures that can be grown indefinitely in the laboratory. Adult stem cells (including adult and umbilical cord blood) stem cells have been identified in many organs and tissues. Typically there is a very small number of multipotent stem cells in each tissue, and these cells have a limited capacity for proliferation, thus making it difficult to generate large quantities of these cells in the laboratory.

Autologous vs Allogeneic Stem Cells

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Autologous cells are cells that come from the same patient and Allogeneic cells are donated cells (cord blood, Amniotic Membrane, Placenta or Dental Pulp) and not from the patient themselves.

Where do Stem Cells Used in Our Treatments Come From?

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We isolated mesenchymal stem cells from peripheral blood. Then cultured MSCs in the special media under sterile condition. This is exclusively for autologous or self-transplants only.

What are induced pluripotent stem (iPS) cells?

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iPS cells are somatic cells that were manipulated to exhibit properties of embryonic stem cells. Introduction of a set of four factors into somatic cells, along with specific culture conditions, alters each cell's epigenetic signature, resetting the cell to a pluripotent ESC-like state. This process is termed "reprogramming." Like ES cells, iPS cells can be differentiated into many different cell types in the lab. IPS cells have been derived from patients affected by a number of diseases, allowing scientists to develop new models of these diseases and screen potential therapeutic agents. iPS cells, therefore, have great potential to contribute to the search for new therapies. Although ES cells remain the gold standard for pluripotency, the scientific community is actively investigating the potential of iPS cells to fulfill many of the research purposes of ESCs. Moreover, if significant safety concerns can be overcome, iPS cells could eventually be valuable to the development of cell-based therapies.

How are the stem cells administered?

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Intravenous (IV)
The safest and simplest method for delivering the stem cell throughout the body. Anesthesia is not required but light anesthesia can be administered if necessary.IV administration usually takes about 20 – 30 minutes.
Intramuscular (IM)
The stem cells are injected directly into the muscle. Intramuscular implantation is very safe and does not require anesthesia.
Intra-articular (IA)
The stem cells are injected directly into the affected joint by a licensed physician. This method is commonly used for arthritis. Intra-articular implantation is quite safe and does not require anesthesia.

How do stem cells work?

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Essentially, stem cells are progenitor cells which are capable of regeneration and differentiation into a wide range of specialized cell types. Once injected, stem cells follow inflammatory signals from damaged tissues and have multiple ways of repairing these damaged areas.

Which kinds of stem cells are used in Stem Cell Institute treatments?

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Mesenchymal Stem Cells ideally suited for treating systemic autoimmune and inflammatory conditions. They also play a significant role in regenerating injured tissue.
They act via anti-inflammatory activity, immune modulating capacity, and the ability to stimulate regeneration.

Between IVF and ICSI which method is more effective?

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Since much research and technology has been done over the years, we find that ICSI creates a higher chance of pregnancy by almost 3 times

Is Freezing Your Egg Necceassry

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For women who would like to keep their eggs for the future or when they are ready, the egg cell when you become older has less quality and have a higher chance for the fetus to develop health issues, so for women who wish to have a child in the future, freezing eggs is the best choice.

Between FISH and PGS chromosomes check, which one is more effective?

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FISH technique is check only 5 chromosomes, 13 18 21 X and Y for screening, while the PGS will check every chromosome Therefore, the chance that the PGS technique will detect chromosomal abnormalities is much higher than the FISH technique.

Is it ok to have sexual intercourse after embryo transfer

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It is not recommend to have sexual intercouse after the embryo transfer for 7 days.

Do sterilized men have sperm?

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Usually, men who has undergone sterilization procedure will still be able to produce sperm, but the sperm cannot travel through the sperm duct. Therefore the TESE method can be used to affectively collect the sperm.

Which method is better between transferring frozen embryo and non-frozen embryo?

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Generally the physician will suggest the patients to freeze their embryo, because for future testing such as the chromosomes test using the PGS method, the embryo should be frozen. Since the PGS method takes around 3-5 days to complete. The embryo that has gone through the PGS test is usually less likely to has any issues, so using frozen embryo is more effective than non-frozen embryo.

What is the factor for a successful pregnancy?

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The success rate for pregnancy is at around 40-60% and it depends on many factors, including medicine that is used, the time that the medicine is applied, their age, and the health and well being both physically and mentally of the patients. These are all factor so to know the exact factor it is best to consult a physician.

What is the right age to get treatment?

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We find that women over 35 years of age will start to have irregularity in their egg cells, therefore the issues can happen more often. Physicians will usually suggest a chormosomes test to decrease the risk.

In the case that I cannot ejaculate in the sperm collection room, what should I do?

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Novavida does not allow men to collect semen outside of our facility for the regulation of sperm trading. Therefore if you are unable to ejaculate, please come back next time. Try your best to relax and ease your anxiety.

How long can embryo be frozen?

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The embryo at out clinic is frozen at -196 celcius, allowing the embryo to be stored up to decades long.

What to do if I forget my injecton?

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In the case that the patients forget their injection, please call the clinic to consult with the physician.
This is strongly advice against since the eggs that could be collected will reduce in number, so we encourage you to remember the injection on the schedule that the physician has adviced.

Can I get Thai massages during my treatment?

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We adviced against it, since the massage might create pressure on certain area of the uterus.